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3 mg/kg daily in 3 divided doses; dosage adjusted to achieve peak serum gentamicin concentrations approximately 3 mcg/mL and trough concentrations <1 mcg/mL. Used in conjunction with penicillin G or ceftriaxone; usual duration is 2 weeks for penicillin-susceptible strains (MIC ≤0.1 mcg/mL), 2 weeks for relatively resistant strains (MIC >0.1 Generic Name Gentamicin DrugBank Accession Number DB00798 Background. Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from Micromonospora purpurea in 1963. 7 It is one of the most frequently prescribed aminoglycosides due to its spectrum of activity, low cost, and availability. 5,8 Gentamicin is effective against both gram-positive and gram-negative organisms but
Gentamicin is an antibiotic that fights bacteria. Gentamicin is used to treat severe or serious bacterial infections. Gentamicin may also be used for purposes not listed in this medication guide.
Gentamicin will not treat a viral infection such as the flu or a common cold. Drink plenty of liquids while you are taking gentamicin. This will help keep your kidneys working properly. While using gentamicin, you may need frequent blood or urine tests. Your hearing, kidney function, and nerve function may also need to be checked.
Gentamicin is an aminoglycoside antibiotic used in the treatment of several gram-negative infections. It should be indicated based on patient age, symptoms, signs at presentation, and local antimicrobial resistance patterns to enhance the probability of successful treatment in bacterial septicemia, meningitis, urinary tract infections, gastrointestinal tract infections, and soft tissue infections.
Gentamicin Sulfate Dosage and Administration. Gentamicin Injection may be given intramuscularly or intravenously. The patient's pretreatment body weight should be obtained for calculation of correct dosage. The dosage of aminoglycosides in obese patients should be based on an estimate of the lean body mass.
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